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Pesquisas Internas

  • Asma Sharkawy

    Asma Sharkawy is a post-doctoral researcher at CBQF working on the development of innovative biodegradable packaging. She received her PhD degree in Chemical and Biological Engineering in 2021 from the Faculty of Engineering at the University of Porto. Before her PhD, Asma obtained her MSc degree in Chemistry from the American University in Cairo, and her BSc degree in Pharmaceutical Sciences from Cairo University. Her PhD thesis focused on the development of novel clean-label Pickering emulsions stabilized with bio-polymeric particles for the encapsulation and delivery of bioactive agents. Her research work involved interdisciplinary research areas, such as the engineering of biopolymeric dispersions, interfaces and colloids, food and sustainable cosmetic applications, drug encapsulation and delivery, as well as functional textiles.

     

    Publications

    Sharkawy, A., Barreiro, M. F., & Rodrigues, A. E. (2022). Pickering emulsions stabilized with chitosan/gum Arabic particles: Effect of chitosan degree of deacetylation on the physicochemical properties and cannabidiol (CBD) topical delivery. Journal of Molecular Liquids, 355, 118993. https://doi.org/10.1016/j.molliq.2022.118993.

    Sharkawy, A., Silva, A. M., Rodrigues, F., Barreiro, F., & Rodrigues, A. (2021). Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles as green topical delivery vehicles for cannabidiol (CBD). Colloids and Surfaces A: Physicochemical and Engineering Aspects, 631, 127677. https://doi.org/10.1016/j.colsurfa.2021.127677

    Sharkawy, A., Casimiro, F. M., Barreiro, M. F., & Rodrigues, A. E. (2020). Enhancing trans-resveratrol topical delivery and photostability through entrapment in chitosan/gum Arabic Pickering emulsions. International Journal of Biological Macromolecules, 147, 150–159. https://doi.org/10.1016/j.ijbiomac.2020.01.057

    Sharkawy, A., Barreiro, M. F., & Rodrigues, A. E. (2019). Preparation of chitosan/gum Arabic nanoparticles and their use as novel stabilizers in oil/water Pickering emulsions. Carbohydrate Polymers, 224. https://doi.org/10.1016/j.carbpol.2019.115190

    Sharkawy, A., Fernandes, I. P., Barreiro, M. F., Rodrigues, A. E., & Shoeib, T. (2017). Aroma-Loaded Microcapsules with Antibacterial Activity for Eco-Friendly Textile Application: Synthesis, Characterization, Release, and Green Grafting. Industrial and Engineering Chemistry Research, 56(19), 5516–5526. https://doi.org/10.1021/acs.iecr.7b00741

  • Catarina Pereira

    Catarina Pereira holds a BSc degree in Biology with a master’s in applied microbiology and is finishing her PhD in systems biology at the University of Lisbon. During her career, she acquired knowledge in Mycobacterium tuberculosis characterization, bioinformatics and molecular biology fields. She is a research scientist in the CBQF (Centro de Biotecnologia e Química Fina) focused on the study of mechanisms that contribute to the persistence of Listeria monocytogenes strains in food contributing to improving food safety. Between health and food microbiology she presents 5 research papers having participated in several international conferences.

     

    Publications

    Pereira C, Mazein A, Farinha C, Gray M, Kunzelmann K, et al. CyFi-MAP: an interactive pathwaybased resource for cystic fibrosis. Scientific Reports. 2021 DOI: 10.1038/s41598-021-01618-3

    Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, et al. Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries. Infect Genet Evol. 2019. DOI: 10.1016/j.meegid.2018.03.011

    Pereira C, Gomes P, Taveira R, Silva C, Maltez F, Macedo R, et al. Insights on the Mycobacterium tuberculosis population structure associated with migrants from portuguese-speaking countries over a three-year period in Greater Lisbon, Portugal: Implications at the public health level. InfectGenet Evol. 2019 DOI: 10.1016/j.meegid.2019.03.025

    Machado D, Coelho TS, Perdigão J, Pereira C, Couto I, Portugal I, et al. Interplay between mutations and efflux in drug resistant clinical isolates of Mycobacterium tuberculosis. Front Microbiol. 2017 DOI: 10.3389/fmicb.2017.00711

    Perdigão J, Maltez F, Machado D, Silva H, Pereira C, Silva C, et al. Beyond extensively drug-resistant tuberculosis in Lisbon, Portugal: a case of linezolid resistance acquisition presenting as an iliopsoas abscess. International Journal of Antimicrobial Agents. 2016 DOI: 10.1016/j.ijantimicag.2016.07.026

  • Hafsae Lamsaf

    Holder of PhD degree, Faculty of Science and Techniques, Fez (Morocco): "Elaboration of new inorganic and organic polyphosphometalic materials: structural studies, spectroscopic characterizations and magnetic properties" (collaboration with Physics center of University of Coimbra & Technical University of Munich (Germany).

    Currently, a postdoctoral researcher in university catolica de Porto-Portugal, working on BioProtect project “Development of packaging material biodegradable with active properties for food preservation”: The production of biodegradable materials with specific functional agents in order to improve gas and moisture barrier properties and mechanical properties compared to current materials, and to give an active role in preserving perishable foods.

     

    Publications

    [1] Lamsaf, H., Ballesteros, L. F., Cerqueira, M. A., Teixeira, J. A., Pastrana, L. M., Rebouta, L., ... &Calderon, S. (2022). Zn and Zn-Fe nanostructures with multifunctional properties as components forfood packaging materials. Nanomaterials, 12(12), 2104. https://doi.org/10.3390/nano12122104

    [2] H. Lamsaf, V.Lenzi, L.Marques, L.Rebouta, S.Carvalho, L.F.Ballesteros, M.A.Cerqueir, J.A.Teixeira, L.Pastrana, .S. Calderon V. (2021). Zn-Fe Flower-like nanoparticles growth by gas condensation. Materials Letters, 297, 129916.

    [3] H. Lamsaf, R. Fausto, B.F.O. Costa, J. Toyir, E.H. Elghadraoui, M. Ijjaali, A. Oulmekki,Mater. Chem.Phys.216(2018) 22–27.  https://doi.org/10.1016/j.matchemphys.2018.05.060

    [4] H. Lamsaf, A. Oulmekki, E.H. Elghadraoui, R. Fausto, B.F.O. Costa, ,J. Phys. Chem. Solids,119
    (2018) 122-125  https://doi.org/10.1016/j.jpcs.2018.03.040

    [5] H. Lamsaf, M.I.L. Soares, S.M.V. Pinto, E.M. Brás, M.S.C. Henriques, J.A. Paixão, A. Oulmekki, E.H. Elghadraoui, R. Fausto, Molecular and crystal structures and spectroscopic properties of 2-oxo-2-(Thiophen-2-yl) ethyl phosphonic acid, Journal of Molecular Structure (2018) doi: https://doi.org/ 10.1016/j.molstruc.2018.10.015

  • Joana Fangueiro

    Joana F. Fangueiro is a pharmaceutic with a Ph.D. in Pharmaceutical Technology from the Faculty of Pharmacy of the University of Coimbra, Portugal (2016). Joana is a Junior Researcher at Alchemy at Biotechnology School of the Portuguese Catholic University (ESB-UCP)/Amyris joint-collaboration project, working on the economic valorization of Amyris’ industrial fermentation coproducts/residues, aiming at developing innovative products for cosmetic, food, animal feed, agricultural, and pharmaceutical applications.
    Her main research experience is focused on biotechnology, namely in the development, characterization and functionalization of nanosystems for biomedical, cosmetic and pharmaceutical applications. During her career, she worked in the field of biomaterials gaining experience in their process and characterization for application drug delivery (oral, dermal and ocular) and regenerative medicine; cell culture techniques and animal studies (FELASA Cat. B certified by DGAV).

    Recently, she was also R&D manager of a cosmetic and fragrance company in Portugal, Braga being responsible for the formulation, stability and security assessment of cosmetics and also supervision of the control quality system.  She has also experience in supervising young researchers (master and pH students) in the academic and industry. She is reviewer of several recognized journals in the field of nanomedicine and pharmaceutical technology.

     

    Publications

    N.O. Monteiro; M.R. Casanova; R.Quinteira; J.F.Fangueiro; R.L.Reis; N.M.Neves, Biomimetic surface topography as a potential modulator of macrophages inflammatory response to biomaterials. Biomaterials Advances 141 (2022): 213128.   https://doi.org/10.1016/j.bioadv.2022.213128.

    Andreani, T.; Dias-Ferreira, J.; Fangueiro, J.F.; Souza, A.L.R.; Kiill, C.P.; Gremião, M.P.D.; García, M.L.; Silva, A.M.; Souto, E.B.. "Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection". Heliyon 6 5 (2020): e03831. https://dx.doi.org/10.1016/j.heliyon.2020.e03831.

    Fangueiro, Joana F.; Calpena, Ana C.; Clares, Beatriz; Andreani, Tatiana; Egea, Maria A.; Veiga, Francisco J.; Garcia, Maria L.; Silva, Amélia M.; Souto, Eliana B.. "Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): In vivo , in vitro and ex vivo studies". International Journal of Pharmaceutics 502 1-2 (2016): 161-169. https://dx.doi.org/10.1016/j.ijpharm.2016.02.039.

    Fangueiro, Joana F.; Andreani, Tatiana; Egea, Maria A.; Garcia, Maria L.; Souto, Selma B.; Silva, Amélia M.; Souto, Eliana B.. "Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity". International Journal of Pharmaceutics 461 1-2 (2014): 64-73. https://dx.doi.org/10.1016/j.ijpharm.2013.11.025.

    Fangueiro, J.F.; Macedo, A.S.; Jose, S.; Garcia, M.L.; Souto, S.B.; Souto, E.B.. "Thermodynamic behavior of lipid nanoparticles upon delivery of Vitamin e derivatives into the skin: In vitro studies". Journal of Thermal Analysis and Calorimetry 108 1 (2012): 275-282. https://www.scopus.com/inward/record.url?eid=2-s2.0-84858082399&partnerID=MN8TOARS

  • João Pedro Bebiano e Costa

    João Costa holds a PhD in Regenerative Medicine, Tissue Engineering and Stem Cells, from the University of Minho, Braga and a MBA in Hospital Administration and Health Management, from the University of Nebrija, Madrid. His research interests focus on the area of Regenerative Medicine and Biofabrication (3D Printing) for the development of orthopedic implants. During his PhD, he was a visiting researcher at two of the most prestigious universities in this field: (1) Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA and (2) University College of London (Orthopedic department), London, UK. He was recently awarded a contract through the Scientific Employment Stimulation Contest – Individual to develop his research project. He has published 27 scientific articles, is the author/co-author of 3 international patents and holds several oral lectures at national and international congresses.

     

    Publications

    Costa J. B, Park J, Jorgensen A. M, Silva-Correia J, Rei, R. L, Oliveira J. M, Atala A, Yoo J, Lee, S. J. 3D Bioprinted Highly Elastic Hybrid Constructs for Advanced Fibrocartilaginous Tissue Regeneration. Chemistry of Materials, 2020, 32(19), 8733-8746.
    https://doi:10.1021/acs.chemmater.0c03556

    Costa J. B, Silva-Correia J, Oliveira J. M, & Reis R. L. Fast Setting Silk Fibroin Bioink for Bioprinting of Patient-Specific Memory-Shape Implants. Advanced Healthcare Materials, 2017, 6(22), 1701021.
    https://doi.org/10.1002/adhm.201701021

    Costa J. B, Silva-Correia J, Ribeiro V. P, da Silva Morais A, Oliveira J. M, & Reis R. L. Engineering patient-specific bioprinted constructs for treatment of degenerated intervertebral disc. Materials Today Communications, 2019, 19, 506-512.
    https://doi.org/10.1016/j.mtcomm.2018.01.011

    Decante G, Costa J. B, Silva-Correia J, Collins M. N, Reis R. L, & Oliveira J M. Engineering bioinks for 3D bioprinting. Biofabrication, 2021, 13(3), 032001.
    https://doi:10.1088/1758-5090/abec2c

    Costa, J. B, Lima M. J, Sampaio M. J, Neves M. C, Faria J. L, Morales-Torres S, …Silva C. G. Enhanced biocatalytic sustainability of laccase by immobilization on functionalized carbon nanotubes/polysulfone membranes. Chemical Engineering Journal, 2019, 355, 974-985.
    https://doi.org/10.1016/j.cej.2018.08.178

  • Raquel Costa

    Raquel Costa holds a PhD in Metabolism: Clinical and Experimental (2017; Faculty of Medicine, UP and University of Santiago de Compostela), which was focused in studying vascular and metabolic alterations in diabetes and to identify molecular mechanisms underlying angiogenesis and metabolism and their modulation by natural-derived compounds. Then, she was a researcher in a tissue regeneration project related with chronic wounds and was a Co-PI of a EIT Health funded project in this field. She participates in an interventional clinical study funded by a European Company, aiming to evaluate the effect of polyphenols on metabolic disease, with University of Vienna. Presently, she is working with biomaterials at CBQF, aiming to study biomaterials (textiles, hydrogels and scaffolds) and stem cells in the context of chronic wounds.

    Raquel is involved in several research projects, published 46 original papers and book chapter, presented her work in +100 scientific meetings and is referee for 9 peer-reviewed journals. Raquel is a lecturer in Biochemistry, and participates in some hands-on post-graduate courses, including the UC in Angiogenesis and metabolism at FMUP and the UC in Tissue engineering and biofabrication at ESB.

     

    Publications

    Batista-Silva S, Bernardes BG, Borges S, Rodrigues I, Fernandes R, Gomes-Guerreiro S, Teixeira-Pinto M, Pintado M, Soares R, Costa R* and Ana Leite Oliveira* (2022). Exploring silk sericin for diabetic wounds: an in situ forming hydrogel to protect against oxidative stress and improve tissue healing and regeneration. Biomolecules 12, 801
    doi: 10.3390/biom12060801

    Mooenfard M, Pena MJ, Barata P, Soares R and Costa R (2022). Anti-angiogenic Activity of Raw and Roasted Date Seed Polyphenol Extracts (Kabkab cultivar) on Human Microvascular Endothelial Cells. Plant Foods for Human Nutrition
    doi: 10.1007/s11130-022-01003-z

    Costa R, Azevedo D, Barata P, Soares R, Guido L, Carvalho D (2021). Phenolic composition, antioxidant and anti-angiogenic in vitro activities of an hydroalcoholic extract obtained from Euterpe oleracea fruit powder supplement Molecules 26(7):2011
    doi: 10.3390/molecules26072011

    Gomes A, Coelho P, Soares R, Costa R (2021). Human Cord Blood Mesenchymal Stem Cells in Type 2 Diabetes Mellitus: the emerging therapeutic approach. Cell Tissue Res 385(3):497-518
    doi: 10.1007/s00441-021-03461-4

    Costa R, Costa L, Rodrigues I, Meireles C, Soares R, Tamagnini P, Mota R (2021).  Biocompatibility of the biopolymer Cyanoflan for applications in skin wound healing. Marine Drugs 19(3):147
    doi: 10.3390/md19030147

  • Srishti Singh

    A Junior researcher in the Universidade Católica Portuguesa, at Porto. I am working in BioProtect Project (Development of packaging material biodegradable with active properties for food preservation). I granted a degree in European MSc in Food Science, Technology, and Business where I worked on the project on Recycling of polypropylene by supercritical CO2. I have also worked in the development of a new method for antibiotic-free decontamination using plasma technology for the preservation of biological tissue at the Forschungsinstitut für Nutztierbiologie in Dummerstorf, Germany did my under graduation in Chemistry, Delhi University where I worked on the project-Computation studies on the interaction of Neurophysin I and oxytocin. These years of academic nourishment in science and being from a rapid-paced developing country I have understood the necessity and urgency of sustainability. The importance of sustainability in the food packaging industry has become a part of my Ikigai, purpose in life.

     

    Publications

    Recycling of polypropylene (PP) by supercritical CO2 for extraction of contaminants from beverage cups. A comparison with polyethylene terephthalate (PET) and polylactic acid (PLA)
    Srishti Singh, Joel Pereira, Teresa Brandão, Ana Leite Oliveira, Fátima Poças
    DOI: 10.1002/jsfa.12213

  • Valter Filipe Reis Martins

    Valter Filipe Reis Martins holds a BSc in Phytofarmacy of Aromatic and Medicinal Plants, a MSc in Farmacy and Chemistry of Natural Products and another MSc in Food Quality and Safety, all degrees from the Escola Superior Agrária de Bragança of the Instituto Politécnico de Bragança.

    Currently, I am a PhD student in Biotechnology, specialization in Food Science and Engineering at the Escola Superior de Biotecnologia – Universidade Católica Portuguesa, working on the topic of Valorization of Microalgae and Agro-industrial By-Products in the Development of Biodegradable Coatings Under a Circular Economy Approach.

     

    Publications

    Martins, V.F.R., Pintado, M.E., Morais, R.M.S.C., Morais, A.M.M.B. (2022) Valorisation of Micro/Nanoencapsulated Bioactive Compounds from Plant Sources for Food Applications Towards Sustainability. Foods, 12, 32. https://doi.org/10.3390/foods12010032

    José Pinela, César Montoya, Ana Maria Carvalho, Valter Martins, Filomena Rocha, Ana Maria Barata, Lillian Barros, Isabel C.F.R. Ferreira (2019) Phenolic composition and antioxidante properties of ex-situ conserved tomato (Solanum lycopersicum L.) germplasm. Food Research International. 2019, 125, 108545. https://doi.org/10.1016/j.foodres.2019.108545

    Mikel Añibarro-Ortega, José Pinela, Ana Ciric, Valter Martins, Filomena Rocha, Marina D. Sokovic, Ana Maria Barata, Ana Maria Carvalho, Lillian Barros, Isabel C.F.R. Ferreira (2020) Valorization of table tomato crop by-products: Phenolic profiles and in vitro antioxidante and antimicrobial activities. Food and Bioproducts Processing. 2020, 124, 307-319. https://doi.org/10.1016/j.fbp.2020.09.006

    Valter Martins, Vania Silva, Sandra Pereira, Silvia Afonso, Ivo Oliveira, Marlene Santos, Carlos Ribeiro, Alice Vilela, Eunice Bacelar, Ana Paula Silva, Berta Goncalves (2021) Rootstock Affects the Fruit Quality of “Early Bigi” Sweet Cherries. Foods. 2021, 10 (10), 2317.  https://doi.org/10.3390/foods10102317

  • Viviana Ribeiro

    Viviana Ribeiro graduated in 2009 from the University of Trás-os-Montes and Alto Douro, in Genetics and Biotechnology. In 2011, concluded her Master degree in Clinical Laboratory Biology from the same institution. In 2018, completed her PhD in Tissue Engineering, Regenerative Medicine and Stem Cells at the University of Minho, in collaboration with the Conselho Superior de Investigacione Científicas (CSIC, Madrid). That same year, integrated two research projects as a postdoctoral fellow at the University of Minho. In 2019, awarded a Junior Doctoral Researcher contract at the same institution.

    Since October 2022, she has been a member of the Centre for Biotechnology and Fine Chemistry (CBQF) of School of Biotechnology (ESB) of the Portuguese Catholic University of Porto, as a Doctorate Junior Researcher, developing research in the scientific area of biotechnology, biomaterials applied in tissue engineering and regenerative medicine. She performs teaching activities to the Master in Biomedical Engineering (ESB, Porto), course unit of Tissue Engineering and Biofabrication.

    Her proficiency resulted in 4 patents, more than 60 publications (articles in international journals, book chapters and conferences) and more than 40 presentations at scientific meetings. She has been involved in the preparation and submission of several national and international project.

     

    Publications

    Book Chapter:

    Ribeiro V.P., Oliveira J.M., and Reis R.L. "Role of Silk Fibroin Biomaterials asArtificial ECM for 3D in vitro Modeling". In Multiscale Cell-BiomaterialsInterplay in Musculoskeletal Tissue Engineering and Regenerative Medicine.Portugal: Elsevier, 2022.Under revision

    Ribeiro V.P.. "Hydrogels for cancer treatment". In Hydrogels for TissueEngineering and Regenerative Medicine, edited by Silva-Correia J., Reis R.L.,and Oliveira J.M. Portugal: Elsevier, 2021.Accepted

    Ribeiro V.P., Oliveira J.M., Reis R.L. "Advanced silk-based biotextiles for boneregeneration applications". In Advances in Material Research and Technology,edited by Ikhmayies S. J.. Springer Publisher, 2020. Accepted

    Ribeiro V.P., Pina S., Oliveira J.M., and Reis R.L. "Silk Fibroin-Based Hydrogelsand Scaffolds for Osteochondral Repair and Regeneration". In OsteochondralTissue Engineering - Nanotechnology, Scaffolding-Related Developments andTranslation, Advances in Experimental Medicine and Biology, edited byOliveira J. M., Pina S., Roman J. S., and Reis R. L.. Springer Publisher, 2018. 10.1007/978-3-319-76711-6_145

    Pina S., Ribeiro V.P., Paiva O.C., Correlo V.M., Oliveira J.M., and Reis R.L. "Tissueengineering scaffolds: Future perspectives". In Handbook of TissueEngineering Scaffolds, edited by Atala A.. Elsevier, 2018. 10.1016/b978-0-08-102563-5.00009-56

    Journal article

    Donate R., Tamaddon M., Ribeiro V.P., Monzón M., Oliveira J.M., and Liu C."Translation through collaboration: practice applied in BAMOS project in in vivotesting of innovative osteochondral scaffolds". Biomaterials Translational 3 2(2022): 102-104. 10.12336/biomatertransl.2022.02.003

    Ribeiro V.P., Costa J.B., Carneiro S.M., Pina S., Veloso A.C.A., Reis R.L., and OliveiraJ.M. "Bioinspired Silk Fibroin-Based Composite Grafts as Bone Tunnel Fillers forAnterior Cruciate Ligament Reconstruction". Pharmaceutics 14 4 (2022). 10.3390/pharmaceutics140406973

    Hurle K., Maia F.R., Ribeiro V.P., Pina S., Oliveira, J.M., Goetz-Neunhoeffer F., andReis R.L. "Osteogenic lithium-doped brushite cements for bone regeneration". Bioactive Materials (2021). 10.1016/j.bioactmat.2021.12.0254

    Lemos R., Maia F.R., Ribeiro V.P., Costa J., Coutinho P., Reis R.L., and Oliveira, J.M."Carbon nanotubes-reinforced cell-derived matrix-silk fibroin hierarchicalscaffolds for bone tissue engineering applications". Journal of MaterialsChemistry B 9 (2021): 9561-9574. 10.1039/D1TB01972D

    Oliveira J.M., Ribeiro V.P., and Reis R.L. "Advances on gradient scaffolds forosteochondral tissue engineering". Progress in Biomedical Engineering (2021). 10.1088/2516-1091/abfc2c.

    Pierantoni L., Ribeiro V.P., Costa L., Pina S., da Silva Morais A., Silva-Correia J.,Kundu S. C., Motta A., Reis R.L.,; and Oliveira J.M. "Horseradish Peroxidase-Crosslinked Calcium-containing Silk Fibroin Hydrogels as Artificial Matrices forBone Cancer Research". Macromolecular Bioscience (2021). 10.1002/mabi.202000425.

    Ribeiro V.P., Pina, S., Gheduzzi S., Araújo A.C., Reis R.L., and Oliveira J.M."Hierarchical HRP-crosslinked silk fibroin/ZnSr-TCP scaffolds for osteochondraltissue regeneration: Assessment of the mechanical and antibacterialproperties". Frontiers in Materials 7 49 (2020): 1-12. 10.3389/fmats.2020.00049.

    Donate R., Monzón M., Ortega Z., Wang L., Ribeiro V.P., Pestana D., Oliveira J.M.,and Reis R.L. "Comparison between calcium carbonate and ß-tricalciumphosphate as additives of 3D printed scaffolds with polylactic acid matrix".Journal of Tissue Engineering and Regenerative Medicine 14 2 (2019): 272-283. 10.1002/term.2990.

    Pina S., Ribeiro V.P., Marques C.F., Maia F.R., Silva T., Reis R.L., and Oliveira J.M."Scaffolding Strategies for Tissue Engineering and Regenerative MedicineApplications". Materials 12 11 (2019): 1824. 10.3390/ma12111824.

    Ribeiro V.P., Pina S., Costa J.B., Cengiz I.F., García-Fernández, L., Fernández-Gutiérrez M.M., Paiva O.C.; Oliveira A.L., San-Román J., Oliveira J.M., and Reis R.L."Enzymatically Cross-Linked Silk Fibroin-Based Hierarchical Scaffolds forOsteochondral Regeneration". ACS Applied Materials & Interfaces 11 4 (2019):3781-3799. 10.1021/acsami.8b21259.
    Geão C., Costa-Pinto A.R., Cunha-Reis C., Ribeiro V.P., Vieira S., Oliveira J.M., ReisR.L., and Oliveira

    A.L. "Thermal annealed silk fibroin membranes for periodontalguided tissue regeneration". Journal of Materials Science: Materials in Medicine 30 2 (2019): 27. 10.1007/s10856-019-6225-y.
    Ribeiro V.P., Pina, S., Canadas R.F., da Silva Morais A., Vilela C., Vieira S., Cengiz, I.F., Reis R.L.,; and Oliveira J.M. "In Vivo Performance of Hierarchical HRP-Crosslinked Silk Fibroin/ß-TCP Scaffolds for Osteochondral TissueRegeneration". Regenerative Medicine Frontiers 1 (2019): e190007. 10.20900/rmf20190007.

    Ribeiro V.P., da Silva Morais A., Maia F.R., Canadas R.F., Costa J.B., Oliveira A.L.,Oliveira J.M., and Reis R.L. "Combinatory approach for developing silk fibroinscaffolds for cartilage regeneration". Acta Biomaterialia 72 (2018): 167-181. 10.1016/j.actbio.2018.03.047.

    Ribeiro V.P., Silva-Correia J., Gonçalves C., Pina S., Radhouani H., Hyttinen J., RoyA., Oliveira A.L., Reis R.L.; and Oliveira J.M.. "Rapidly responsive silk fibroinhydrogels as an artificial matrix for the programmed tumor cells death". PLOSONE 13 4 (2018): e0194441. 10.1371/journal.pone.0194441.

    Monzón M., Liu C., Ajami S., Oliveira J.M., Donate R., Ribeiro V.P., and Reis R.L."Functionally graded additive manufacturing to achieve functionalityspecifications of osteochondral scaffolds". Bio-Design and Manufacturing 1 1(2018): 69-75. 10.1007/s42242-018-0003-4.

    Costa J.B., Silva-Correia J., Ribeiro V.P., da Silva Morais A., Oliveira J.M., and ReisR.L.. "Engineering patient-specific bioprinted constructs for treatment ofdegenerated intervertebral disc". Materials Today Communications (2018). 10.1016/j.mtcomm.2018.01.011.

    Ribeiro V.P., Silva-Correia J., Nascimento A.I., da Silva Morais A., Marques A.P.,Ribeiro A. S., Silva C.J.; Bonifácio G., Sousa R.A., Oliveira J.M., Oliveira A.L., andReis R.L. "Silk-based anisotropical 3D biotextiles for bone regeneration".Biomaterials 123 (2017): 92-106. 10.1016/j.biomaterials.2017.01.027.

    Patents

    Ribeiro V.P., Silva-Correia J., Oliveira J.M., and Reis R.L. 2022. "Carbonicanhydrase-immobilizing silk hydrogels, methods of production and usesthereof (WO 2022/029739 A1)".

    Carvalho M.R., Caballero D., Carvalho C.R., Costa J.B., Ribeiro V.P., Olivera J.M.,Kundu, S.C., and Reis R.L. 2021. "Enzymatically crosslinked silk fibroin hydrogelmicrofluidic platform, methods of production and uses thereof (WO2021/038507 A1)".

    Pina S., Ribeiro V.P., Reis R.L., and Oliveira J.M. 2018. "Ionic-doped compositionmethods and uses thereof (WO 2018/215997 A1)".

    Carvalho C.R., Costa J.B., Ribeiro V.P., Silva-Correia J., Oliveira J.M., and Reis R.L.2018. "Nerve guidance conduits, methods of production and uses thereof (WO2018/025186 A1)".

  • Cláudia Suellen Ferro de Oliveira

    Cláudia S Oliveira has a Degree in Biological Sciences, a post-graduation in Microbiology, and a Master in Pathology of Tropical Diseases. In 2016, completed her PhD in Pathology and Molecular Genetics at University of Porto (Institute of Biomedical Sciences Abel Salazar). After that, integrated the COMPASS Research Group, at University of Aveiro. At this time, she participated in 2 ERC grants and 7 FCT projects in the scope of inspired biomaterials and stem cells aiming to develop 3D humanized platforms with high biological complexity.

    Since October 2022, she is a member of the Centre for Biotechnology and Fine Chemistry (CBQF) of School of Biotechnology (ESB) of the Portuguese Catholic University of Porto, as a Doctorate Junior Researcher, interested in exploring bio-based materials and bioactive agents with antimicrobial, anti-oxidant, and regenerative properties for biomedical and textile applications.

    Her expertise in Molecular Biology, Microbiology, Genetics, and Tissue Engineering resulted in several international publications (book, book chapter, articles, and conferences) and 1 patent deposition. She also has supervised and co-supervised degree, master, and PhD students.

     

    Publications

    Book chapter and book

    Cazzanelli G, Moreira T, Oliveira CS, Azevedo-Silva J, Nogueira E, Preto A. Colorectal cancertherapeutic approaches: from classical drugs to new nanoparticles. Frontiers in Anti-Cancer Drug Discovery, 2016, Vol.7, 93-173.

    Paixão GC, Pantoja LDM, Mourão CL, Oliveira CS (2012). Ensino de Microbiologia através de experimentos práticos. 2012, Edition 1, Imprima conosco, v. 1, 137p.

    Journal article

    Oliveira CS*, Nadine S, Gomes MC, Correia CR, Mano JF*. Bioengineering human bone marrow in liquefied micro-compartments: a promising approach for the recapitulation of osteovascular niches. Acta Biomaterialia, 2022, 149:167-178. https://doi.org/10.1016/j.actbio.2022.07.001

    Jesus D, Pinho AR, Gomes MC, Oliveira CS*, Mano JF*. Emerging modulators for osteogenic differentiation: a combination of chemical and topographical cues for bone microenvironment engineering. Soft Matter, 2022, 18(16): 3107 – 3119. https://doi.org/10.1039/D2SM00009A

    Oliveira CS*, Carreira M, Correia CR, Mano, JM*. The therapeutic potential of hematopoietic stem cells in bone regeneration. Tissue Engineering Part B: Reviews, 2022, 28(2): 379 – 392. https://doi.org/10.1089/ten.teb.2021.0019

    Oliveira CS, Leeuwenburgh S, Mano JM. New insights into the biomimetic design and biomedical applications of bioengineered bone microenvironments. APL Bioengineering, 2021, 5(4). https://doi.org/10.1063/5.0065152

    Gomes MC, Costa D, Oliveira CS*, Mano JF*. Design of protein-based liquified cell-laden capsules with bioinspired adhesion for tissue engineering. Advanced Healthcare Materials, 2021, 10(19). https://doi.org/10.1002/adhm.202100782

    Gomes SD*, Oliveira CS*, Barreto J, Azevedo-Silva J, Pereira H, Chaves SR, Baltazar, F, Côrte-Real M, Preto A. The role of diet related short-chain fatty acids in colorectal cancer metabolism and survival:  prevention and therapeutic implications.  Current Medicinal Chemistry, 2020, 27(24):4087-4108, doi: 10.2174/0929867325666180530102050.

    Oliveira CS, Azevedo-Silva J, Casal M, Côrte-Real M, Baltazar F, Preto A. Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. Oncotarget, 2016, 7(43): 70639-70653.

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